Robert B. Gregory
Assistant Professor
Department of Chemistry
(260) 481-6298
Education:
Doctor of Philosophy in Analytical Chemistry November
1983
Thesis:
Time Resolved Spectroscopy via a
Fast Photon Counting Phase Fluorimeter
Summary: Electronic and optical design, construction,
and characterization of ultra-high
frequency correlation instrument for the phase discrimination of fluorescence
lifetimes via photon counting detection and sine-modulated argon laser
excitation. Modulation rates of up to 300 megahertz resulted in time
resolutions as small as 60 picoseconds with concentration linearity over six
orders of magnitude.
Bachelor of Science in Chemistry August
1978
Research: Wisconsin Department of Natural
Resources-associated study of suspended metal particulates in air, metal
content in water, and data conversion programming for the interface of DNR
computer data to standard data handling packages.
Academic Appointments:
Position: Assistant
Professor August
2005 to Present
Supervisor: Dr.
Ron Friedman, Department Chair
Courses: Analytical
Chemistry, General Chemistry Laboratory.
Research: Combustion
of Organic Molecules in Oxygen Deprived Environments; Isomeric analyses of
substituted peptides and amino acids by vibrational spectroscopy; Analogical
reasoning in chemistry education; Voice and vocal prosody analysis in teaching
efficacy. Consultation to pharmaceutical compounding industry
on analysis of preparations.
Position: Visiting
Associate Professor August
2004 to May 2005
Supervisor: Dr.
Jeffrey Pribyl, Department Chair
Courses: General
Chemistry, Industrial Chemistry, Labs for Biochemistry and Organic Chemistry.
Position: Teaching Assistant,
General Chemistry 115/116 August1982
to December 1983
Supervisor: Joyce
Lytle
Instructor: Dr.
George Bodner, Dr. Fred Lytle, Dr. William Robinson
Position: Research Fellowship June
1980 to August 1982
Advisor: Dr.
Fred Lytle
Position: Teaching Assistant,
Advanced General Chemistry 117/126 August
1978 to May 1980
Instructors: Dr.
Derek Davenport, Dr. Russ Lengel, Dr. Norbert Porile, Dr. William Robinson, Dr. Stuart Tobias
Industrial
Employment:
|
Bioanalytical
Systems, BAS Analytics Division |
|
Position: Senior
Scientist October
2001 to August 2004
Responsible for the daily technical and administrative operation of one of
three teams within a pharmaceutical contract research organization. The
projects within the lab are centered on both stability studies of finished
dosage forms and drug substances of commercial and investigational materials,
and on the development and validation of analytical methods for those
determinations.
|
E-Ink Corporation, |
|
Position: Manager of Analytical Services March
2000 to October 2001
Responsible for the laboratory effort in the analysis of electrophoretic
inks and devices for “electronic paper” applications. Responsibility
for technical leadership, both at the bench and in supervision, toward problem
resolution and fundamental research into the physical, chemical, and
electro-optic parameters of devices. Designed and staffed the analytical
chemistry laboratory. Generated all systems for the control
of quality of the display product line. Developed and validated the
methodology used in both the assessment of quality and in the investigation of
fundamental phenomena and product-oriented issues.
|
Abbott Laboratories, |
|
Position: Project Manager March
1999 to March 2000
Responsible for the design, specification, funding, and implementation of a new
statistically based LIMS system to evaluate and manage out-of-specification results
for environmental laboratories in two divisions. The system was designed to
handle all analytical results for the production of all water (purified, WFI,
and sterile water) for manufacturing in the Specialty Products Division and the
Abbott Diagnostics Division. A new support system was designed that gave the
laboratory management total control over the management of specifications,
method authorship, management of exception handling and reporting, addition of
new levels of exception handling and re-qualification, statistical quality
control, and control of documentation and workflow.
Position: Group Leader April
1992 to March 1999
Leading three to six chemists responsible for all
analytical methodology and documentation to support regulatory filings for drug
substance submissions, both from within the company, and in collaboration with
custom manufacturing customers. Performed and led the methods development
efforts for numerous drug substances, resulting in five ANDA or ANADA submissions,
and supporting three NDA submissions for formulated product.
Research: Developed a rapid
thermal analysis technology for determining the physical properties of precious
samples to avoid the need for large sample quantities during analysis.
Developed and implemented a rapid, rugged, and reliable approach to reducing
the cycle time associated with identity testing for the division. The estimated
savings paid for the capital investment in one year.
Implemented capillary electrophoresis for the analysis of nitroprusside, an inorganic pharmaceutical which
inter-converts between itself and impurities during the course of analysis by
normal methods. The improved method provided detection limits beyond
those required by the USP, and combined one HPLC, one titration, and two
spectroscopic methods into
Responsible for the development of programs for compliance in
the areas of validation, computerization, and operation of laboratory
equipment. Wrote the divisional operating procedure
and policies for laboratory equipment qualification and laboratory computer
validation. Chaired the corporate committee on
laboratory equipment qualification.
|
American Colloid, |
|
Position: Director
of Laboratory Services, American Colloid Company June 1991 to February 1992
Responsibility for the laboratory R&D effort of the company, and the
financial, personnel, and strategic and technical management of a department of
eleven people.
Position: Manager
of Research and Development, Chemdal Corporation January 1990 to June 1991
Management of a department of four to six others responsible for all product
and process R&D.
|
Stepan
Company, |
|
Position: Senior
Research Chemist in Analytical Research November
1983 to January, 1990
Supervision
and project management of three to five scientists in analytical methods
development. Created
several innovative quantitative spectroscopic techniques to improve
productivity for quality control measurements.
Publications:
Invited Paper, Two Photon Excited
Fluorescence; F.E. Lytle, R.B. Gregory, M. Johnson; Federation
of Analytical Chemistry and Spectroscopy Societies, September 1981,
Philadelphia, PA
A Laser Based Cross-Modulation
Spectrometer; R.B. Gregory, F.E. Lytle; The
Time Resolved Spectroscopy via a Fast
Photon Counting Phase Fluorimeter; R.B. Gregory,
thesis publication, University Microfilms, January 1984
Volatile Components Analysis by
TGA-FTIR; R.B. Gregory, Abbott Corporate Technology Exchange, June 1997
The Determination of Nitrate, Nitrite,
Ferricyanide and Ferrocyanide
in Sodium Nitroprusside by Capillary Electrophoresis;
C. Furman, C. McEntegart, R. Gregory; American
Chemical Society National Meeting, April 1999
FTIR Identity Analysis with No Sample
Preparation as a Replacement for Traditional Techniques; R.B. Gregory, P.A. Penelle, C.E. McEntegart, Abbott
Corporate Technology Exchange, June 1999
Statistical
Evaluation of Surfaces and Chemical Class on Cleaning Analysis; G. Murphy, R.B.
Gregory, Abbott Corporate Technical Exchange, June 1999
Web-Based Reporting of
System
and Process for Feedback Speech Instruction,
Grants:
Development
and Evaluation of Guided Inquiry Materials for a Chemistry Course to Prepare
Students to Take College Chemistry, Pribyl J., Hadley M., Gregory, R; Proposal for
NSF CCLI Type 1, November 2004.
Consulting:
Pharmaceutical
Analysis for Pharmacy Preparations –
Memberships:
American Chemical Society
American Optical Society
Council on Undergraduate Research
National Science Teachers Association
Science Education Foundation of