History

A 13-year-old girl who had previously been in good health with very strong performance in school presented with a two-year history of declining school performance and decreasing cognitive ability. She also displayed increasing difficulty with motor activities, which became apparent through her participation in sports.

Past medical history was unremarkable, with no hospitalizations, surgeries or serious illnesses. Family history revealed that her two siblings were in good general health. The patient's father, paternal uncle and paternal grandmother had been diagnosed with a movement disorder in the past.

Two years after the initial presentation the patient's physical and mental condition had deteriorated significantly. Her coordination and movement control worsened and she suffered from depression complicated by an acute psychotic episode. She is currently being maintained on antipsychotic medication and is receiving psychotherapy. No effective treatment was available for her disorder of coordination and movement control.